Pharmacotherapy and cognitive behavioral therapy are efficacious
treatments of depression among diverse groups, however adherence to
medication, adherence to CBT homework, and appointment attendance are
barriers to effective treatmen in the community, particularly among
low income populations. This line of research seeks to investigate
whether text messaging (SMS) can be used to improve adherence to
treatment for depression by sending medication and appointment
reminders along with using SMS as a medium for CBT homework completion
to reinforce thought tracking and behavioral activation. This project
is currently in the initial feasibility/usability stage in preparation
for a randomized trial.
Internet World Health Research
Smoking Cessation Web Study: Tomando Control
The Tobacco Related Disease Research Program funded the establishment
of the Spanish/English Web Site for Smoking Cessation Trials at www.stopsmoking.ucsf.edu
. This project of the University of California, San Francisco/San Francisco
General Hospital Latino Mental Health Research Program is being conducted
in collaboration with the University of California, San Francisco Medical
Effectiveness Research Center for Diverse Populations (MERC) and the University
of California, San Diego. During Phase I of the study, we created the
basic site and tested its ability to 1) recruit participants, 2) obtain
informed consent, 3) obtain initial assessment data, 4) provide one intervention,
and 5) obtain follow-up data, all with minimal human intervention. We
recruited over 4500 smokers, of whom over 1000 were Spanish-speaking.
Tobacco-Related Disease Research Program Grant # 10RT-0326
“Spanish/English web site for smoking cessation trials.”
Principal Investigator: Ricardo F. Muñoz, Ph.D.
During Phase III, we compared four methods to stop smoking via the Web in a randomized control trial. Publications from this phase include:
Muñoz RF, Barrera AZ, Delucchi K, Penilla C, Torres LD, Pérez-Stable EJ. International Spanish/English Internet smoking cessation trial yields 20% abstinence rates at 1 year. Nicotine Tob Res. 2009 Sep;11(9):1025-34. Epub 2009 Jul 29.
Torres LD, Barrera AZ, Delucchi K, Penilla C, Pérez-Stable EJ, Muñoz RF. Quitting smoking does not increase the risk of major depressive episodes among users of Internet smoking cessation interventions. Psychol Med. 2009 Jul 23;:1-9 [Epub ahead of print]
Barrera AZ, Pérez-Stable EJ, Delucchi KL, Muñoz RF. Global reach of an Internet smoking cessation intervention among Spanish- and English- speaking smokers from 157 countries. Int J Environ Res Public Health. 2009 Mar;6(3):927-40. Epub 2009 Feb 26.
Depression Management Course
Yan Leykin, Ph.D.
Untreated depression accounts for more than 11% of the world total disease burden. Depression is associated with up to 60% of suicide deaths, deteriorating health, and social problems. Most affected individuals are not receiving adequate treatment. The long-term objective of this project is to address the issue of untreated depression by developing and evaluating an effective Web-based intervention for depression, available at no cost and in multiple languages to depressed and dysphoric individuals anywhere in the world.
The current project is the first step towards that goal. We have developed a self-contained, interactive, modular, Web-based self-help intervention for depression. The intervention is based on cognitive-behavioral therapy, an empirically supported treatment for depression. Participants from the Internet community are invited to sign up for a customized eight-lesson intervention. This is a proof-of-concept study, with the goal of assessing the degree of interest in and the demand for Web interventions, and to obtain initial information about the effectiveness of this intervention.
We are currently recruiting participants:https://ihrc.ucsf.edu/